大学生社会时差和睡眠质量与心血管代谢风险的关联

大学生社会时差和睡眠质量与心血管代谢风险的关联

作者：陈玉明，陶舒曼，邹立巍，杨娅娟，谢阳，李婷婷，张丹，曲杨，翟爽，陶芳标，伍晓艳

来源：中国学校卫生

英文摘要：

Objective：To explore the association of social jetlag(SJL) and sleep quality with cardiometabolic risk in college students,so as to provide evidence for providing the physical health of college students.

Methods:convenience sampling and cluster sampling method was used to select 318 college students from two universities in Hefei, Anhui Province and Shangrao, Jiangxi Province for questionnaire survev and physical examination from May to June 2021. A self-rated questionmaire was used to investigate the bedtime and wake-up time of college students on weekdays and weekend. SJL was calculated according to the midpoint ofsleep on weekdays and weekend. The Pittsburgh Sleep Ouality lndex was used to evaluate sleep quality among college students. According to the results of biochemical blood tests, blood pressure and human morphology, the cardiometabolic indexes of college students were determined, and the cardiometabolic risk score was calculated, Mann-Whitney U and Kruskal-Walis H rank-sumtests were used to compare the differences of cardiometabolic risk scores among college students with different demographic characteristics. Generalized linear models were used to analyse the association between SJL, sleep quality and cardiometabolic risk scores.

Results:The cardiometabolic risk score for college students was -0.59( -1.85, 1.11). The results of the generalized linear models indicated that both SJL>2 h (β=1.03, 95%CI=0.04-2.03) and poor sleep quality(β=1.67,95%CI=0.46-2.87) were positivel correlated with the cardiometabolic risk score of the college students ( P<0.05). After adjusting for covarates including sex, smoking, alcohol consumption, sleep time type and sleep duration, there were positive correlation between SJL>2 h (β=1.20, 95%CI=0.04-2.03) and poor sleep quality (β=1.82,95%6CI=0.55-3.08) with cardiometabolic risk scores of college students ( P<0.05).

Conclusions:Higher SJL and poor sleep qualily in college students are associated with cardiometabolic risk scores.

中文摘要：

目的：探讨大学生社会时差（SJL）和睡眠质量与心血管代谢风险之间的关联ꎬ为改善大学生身体健康提供依据。

方法：于 2021年 5-6月采用方便抽样和整群抽样方法抽取安徽省合肥市和江西省上饶市2 所高校的 318 名大学生进行问卷调查和体检。使用自评问卷调查大学生工作日和休息日的就寝时间与起床时间,并根据工作日睡眠中点和休息日睡眠中点计算SJL，使用匹兹堡睡眠质量量表评价大学生睡眠质量。根据生化检查、血压和人体形态学测量结果,获得大学生心血管代谢相关指标并计算心血管代谢风险评分。使用Mann-Whitney U和 Kuskal-WallsH秩和检验比较不同人口统计学特征大学生心血管代谢风险评分差异,用广义线性模型分析SJL和睡眠质量与心血代谢风险评分的关联。

结果：大学生的心血管代谢风险评分为-0.59(-1.85,1.11)分。广义线性模型结果显示,SIL>2 h(β=1.03, 95%CI=0.04~2.03)和睡眠质量差(β=1.67, 95%CI=0.46~2.87)与大学生心血管代谢风险评分均呈正相关(P值均<0.05);调整性别、吸烟、饮酒、睡眠时型和睡眠时长等协变量后,SIL>2(β=1.20, 95%CI=0.04~2.03)和睡眠质量差(β=1.82, 95%CI=0.55~3.08)与大学生心血管代谢风险评分均呈正相关(P值均<0.05)。

结论：大学生较高SJL和睡眠质量差与心血管代谢风险评分存在关联。